1334296-12-6
1334296-12-6
Chemical Structure
Seribantumab
Synonym(s): SAR256212; MM 121
- CAS No.: 1334296-12-6
- Formula:N/A
- Molecular Weight:(143.14 kDa)
IUPAC Name: 2-bromo-4,6-dichloro-3-fluoroaniline
SMILES: [Seribantumab]
Biological Activity: Seribantumab (MM 121) is a fully human IgG2 monoclonal antibody that targets HER3. Seribantumab blocks the activation of epidermal growth factor receptor (ErbB) family members and its downstream signal. Seribantumab inhibits neuregulin 1 (NRG1) fusion-dependent tumorigenesis in vitro and in vivo in breast, lung and ovarian patient-derived cancer models[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Seribantumab | 96.043% | Seribantumab (MM 121) is a fully human IgG2 monoclonal antibody that targets HER3. Seribantumab blocks the activation of epidermal growth factor receptor (ErbB) family members and its downstream signal. Seribantumab inhibits neuregulin 1 (NRG1) fusion-dependent tumorigenesis in vitro and in vivo in breast, lung and ovarian patient-derived cancer models. | ||||||||||||||||||||
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