1338055-88-1
Chemical Structure
Colistin B sulfate
Synonym(s): Polymyxin E2 sulfate
- CAS No.: 1338055-88-1
- Formula:C52H98N16O13.xH2SO4
- Molecular Weight:1155.43 (free base)
SMILES: CC(C)CCCCC(N[C@@H](CCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCN)C(N[C@@H]1C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@](C(NCC1)=O)([H])[C@H](O)C)=O)CCN)=O)CCN)=O)CC(C)C)=O)CC(C)C)=O)CCN)=O)=O)=O)=O)=O.O=S(O)(O)=O.[x]
Biological Activity: Colistin B (Polymyxin E2) sulfate is a major component of Colistin (HY-113678) and also an antibacterial agent active against multidrug-resistant Gram-negative bacteria. Colistin B sulfate exerts apoptotic effects on human renal proximal tubular cells. Colistin B sulfate induces mild to moderate renal histological damage in mouse models. Colistin B sulfate can be used in the research of multidrug-resistant Gram-negative bacterial infections[1].
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Colistin B sulfate | Colistin B (Polymyxin E2) sulfate is a major component of Colistin (HY-113678) and also an antibacterial agent active against multidrug-resistant Gram-negative bacteria. Colistin B sulfate exerts apoptotic effects on human renal proximal tubular cells. Colistin B sulfate induces mild to moderate renal histological damage in mouse models. Colistin B sulfate can be used in the research of multidrug-resistant Gram-negative bacterial infections. | |||||||||||||||||||||
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