1338380-52-1
1338380-52-1
Chemical Structure
Carotegrast methyl hydrochloride
Synonym(s): AJM300 hydrochloride
- CAS No.: 1338380-52-1
- Formula:C28H26Cl2N4O5.xHCl
- Molecular Weight:569.44 (free base)
SMILES: O=C([C@@H](NC(C1=C(C=CC=C1Cl)Cl)=O)CC2=CC=C(C=C2)N3C(N(C4=C(C3=O)C=C(C=C4)N(C)C)C)=O)OC.Cl.[x]
Biological Activity:
Carotegrast methyl (AJM300) hydrochloride is an orally active and selective α4 integrin antagonist. HCA2969, an active metabolite of Carotegrast methyl hydrochloride, is a specific and dual α4β1/α4β7 integrin antagonist. Carotegrast methyl hydrochloride prevents the development of colitis in mice[1].
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Carotegrast methyl hydrochloride | Carotegrast methyl (AJM300) hydrochloride is an orally active and selective α4 integrin antagonist. HCA2969, an active metabolite of Carotegrast methyl hydrochloride, is a specific and dual α4β1/α4β7 integrin antagonist. Carotegrast methyl hydrochloride prevents the development of colitis in mice. |
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