1343476-44-7
Chemical Structure
Val-Ala-PAB
- CAS No.: 1343476-44-7
- Formula:C15H23N3O3
- Molecular Weight:293.37
IUPAC Name: (S)-2-amino-N-((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)-3-methylbutanamide
InChIKey: NNWYWNRCBPYLML-GWCFXTLKSA-N
SMILES: CC(C)[C@H](N)C(N[C@@H](C)C(NC1=CC=C(C=C1)CO)=O)=O
Biological Activity: Val-Ala-PAB is a cleavable ADC linker that can be used for ADCs synthesis[1].
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Val-Ala-PAB | 99.70% | Val-Ala-PAB is a cleavable ADC linker that can be used for ADCs synthesis. | ||||||||||||||||||||
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Val-cit-PAB-OH (GMP) | Val-cit-PAB-OH GMP is a GMP grade Val-cit-PAB-OH (HY-12362). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Val-cit-PAB-OH is a degradable ADC linker. | |||||||||||||||||||||
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Ala-Ala-Asn-PAB | Ala-Ala-Asn-PAB is a peptide cleavable ADC linker for antibody-drug conjugates (ADCs). | |||||||||||||||||||||
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Boc-Val-Ala-PAB | 99.98% | Boc-Val-Ala-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate (ADCs). | ||||||||||||||||||||
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4-Pentynoyl-Val-Ala-PAB | 4-Pentynoyl-Val-Ala-PAB is a click chemical class ADC linker. Click chemistry has good biological orthogonality characteristics: biocompatible, fast and highly specific in the biological environment, and has great application potential in the binding between nucleic acids, lipids, proteins and other molecules. | |||||||||||||||||||||
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L-Val-D-Cit-PAB | L-Val-D-Cit-PAB is an ADC linker, and can be used for synthesis of ADCs. | |||||||||||||||||||||
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D-Val-L-Cit-PAB | D-Val-L-Cit-PAB is an ADC connector that can be used to construct ADCs. | |||||||||||||||||||||
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Lys-Ala-pNA | 99.83% | Lys-Ala-pNA is hydrolytic substrate the of dipeptidyl peptidase (DPP) II with Km of 0.42 mM. | ||||||||||||||||||||
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H-Val-Ala-pNA | H-Val-Ala-pNA is a substrate for the dipeptide aminopeptidase (DPAPase) of Streptococcus bovis. H-Val-Ala-pNA can be used to measure the activity of the protease. | |||||||||||||||||||||
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L-Valine p-nitroanilide | L-Valine p-nitroanilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development. | |||||||||||||||||||||
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Alloc-Val-Ala-pAB | 98.02% | Alloc-Val-Ala-PAB is a peptide cleavable linker used in the synthesis of antibody-drug conjugates (ADCs). The Val-Ala will specifically be cleaved by Cathepsin B. The Alloc group is stable to treatment with piperidine and TFA, but can be easily removed under mild conditions by palladium catalyzed allyl transfer. | ||||||||||||||||||||
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