1346523-18-9
Chemical Structure
3'-Deoxy-3'-fluorothymidine-d3
- CAS No.: 1346523-18-9
- Formula:C10H10D3FN2O4
- Molecular Weight:247.24
IUPAC Name: 1-((2R,4S,5R)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(methyl-d3)pyrimidine-2,4(1H,3H)-dione
InChIKey: UXCAQJAQSWSNPQ-BXKFBODDSA-N
SMILES: O=C1C(C([2H])([2H])[2H])=CN(C(N1)=O)[C@H]2C[C@@H]([C@H](O2)CO)F
Biological Activity: 3'-Deoxy-3'-fluorothymidine-d3 is the deuterium labeled Alovudine (HY-B1516). Alovudine (3'-Fluoro-3'-deoxythymidine) is a mtDNA synthesis inhibitor and a marker of DNA synthesis. Alovudine is less susceptible to inflammatory changes than 18F-Fluorodeoxyglucose (FDG) and thus is a better biomarker in pancreatic cancer. Alovudine shows anti-orthopoxvirus and anti-leukemic activity[1][2][3][4][5][6].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
3'-Deoxy-3'-fluorothymidine-d3 | 3'-Deoxy-3'-fluorothymidine-d3 is the deuterium labeled Alovudine (HY-B1516). Alovudine (3'-Fluoro-3'-deoxythymidine) is a mtDNA synthesis inhibitor and a marker of DNA synthesis. Alovudine is less susceptible to inflammatory changes than 18F-Fluorodeoxyglucose (FDG) and thus is a better biomarker in pancreatic cancer. Alovudine shows anti-orthopoxvirus and anti-leukemic activity. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Alovudine | 99.78% | Alovudine (3'-Fluoro-3'-deoxythymidine) is a mtDNA synthesis inhibitor and a marker of DNA synthesis. Alovudine is less susceptible to inflammatory changes than 18F-Fluorodeoxyglucose (FDG) and thus is a better biomarker in pancreatic cancer. Alovudine shows anti-orthopoxvirus and anti-leukemic activity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
