13466-38-1
13466-38-1
Chemical Structure
5-Bromopyridin-2-ol
- CAS No.: 13466-38-1
- Formula:C5H4BrNO
- Molecular Weight:174.00
IUPAC Name: 5-bromopyridin-2(1H)-one
InChIKey: NDMZZQRNZFWMEZ-UHFFFAOYSA-N
SMILES: O=C1C=CC(Br)=CN1
Biological Activity: 5-Bromopyridin-2-ol is a brominated pyridinol (2-pyridone) starting material and synthetic building block. 5-Bromopyridin-2-ol is used in the synthesis of the MNK1/2 inhibitor SEL201 (HY-112113) and the DDX3 inhibitor 7-AID[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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5-Bromopyridin-2-ol | 99.53% | 5-Bromopyridin-2-ol is a brominated pyridinol (2-pyridone) starting material and synthetic building block. 5-Bromopyridin-2-ol is used in the synthesis of the MNK1/2 inhibitor SEL201 (HY-112113) and the DDX3 inhibitor 7-AID. | ||||||||||||||||||||
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References
- [1]. Zhan Y, et al. MNK1/2 inhibition limits oncogenicity and metastasis of KIT-mutant melanoma. J Clin Invest. 2024 Apr 15;134(8):e181338.
- [2]. Doneti R, et al. Molecular docking, synthesis, and biological evaluation of 7-azaindole-derivative (7AID) as novel anti-cancer agent and potent DDX3 inhibitor:-an in silico and in vitro approach. Medical oncology (Northwood, London, England). 2022 Sep 01;39(11):179.
