1348433-02-2
1348433-02-2
Chemical Structure
NAT6-297775
- CAS No.: 1348433-02-2
- Formula:C25H36N6O2
- Molecular Weight:452.60
IUPAC Name: (2S,3aR,6S,6aR)-N-(cyclohexylmethyl)-6-(5-(3-(pyrrolidin-1-ylmethyl)phenyl)-1H-tetrazol-1-yl)hexahydrofuro[3,2-b]furan-2-amine
InChIKey: LFRRGQXSMKOSOQ-UARRHKHWSA-N
SMILES: N(CC1CCCCC1)[C@H]2O[C@@]3([C@H](CO[C@@]3(C2)[H])N4C(=NN=N4)C5=CC(CN6CCCC6)=CC=C5)[H]
Biological Activity: NAT6-297775 (Compound 29) is a protein tyrosine phosphatase (PTP) inhibitor targeting non-receptor PTP SHP-2 with an IC50 of 2.5 μM. NAT6-297775 can inhibit the RAS/MAP kinase signaling pathway. NAT6-297775 can be used for the research of cancer, such as leukemia[1].
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NAT6-297775 | NAT6-297775 (Compound 29) is a protein tyrosine phosphatase (PTP) inhibitor targeting non-receptor PTP SHP-2 with an IC50 of 2.5 μM. NAT6-297775 can inhibit the RAS/MAP kinase signaling pathway. NAT6-297775 can be used for the research of cancer, such as leukemia. | |||||||||||||||||||||
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