1350028-90-8
Chemical Structure
Multiflorin A
- CAS No.: 1350028-90-8
- Formula:C29H32O16
- Molecular Weight:636.55
InChIKey: KXOPSQZLBRPJGX-KEBUVGJQSA-N
SMILES: O=C1C2=C(O)C=C(O)C=C2OC(C3=CC=C(C=C3)O)=C1O[C@H]4[C@@H]([C@@H]([C@H]([C@@H](O4)C)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)COC(C)=O)O)O
Biological Activity: Multiflorin A is an orally active active ingredient of traditional herbal laxative, Pruni semen. Multiflorin A inhibits aromatase enzyme activity with an IC50 of 15.5 μM. Multiflorin A also inhibits quinone reductase 2 (QR2) and COX-2 enzyme. Multiflorin A has purgative activity and reduces postprandial blood glucose in mice. Multiflorin A modulates intestinal glucose transporters, tight junction proteins, and aquaporins, reshapes gut microbiota, and alters faecal metabolites. Multiflorin A can be used for the research of constipation and diabetes[1][2].
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Multiflorin A | Multiflorin A is an orally active active ingredient of traditional herbal laxative, Pruni semen. Multiflorin A inhibits aromatase enzyme activity with an IC50 of 15.5 μM. Multiflorin A also inhibits quinone reductase 2 (QR2) and COX-2 enzyme. Multiflorin A has purgative activity and reduces postprandial blood glucose in mice. Multiflorin A modulates intestinal glucose transporters, tight junction proteins, and aquaporins, reshapes gut microbiota, and alters faecal metabolites. Multiflorin A can be used for the research of constipation and diabetes. | |||||||||||||||||||||
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References
- [1]. Zhao Z, et al. A novel purgative mechanism of multiflorin A involves changing intestinal glucose absorption and permeability. Phytomedicine. 2023;114:154805. [Content Brief]
- [2]. Yang JH, et al. Isolation and evaluation of kaempferol glycosides from the fern Neocheiropteris palmatopedata. Phytochemistry. 2010;71(5-6):641-647.
