1351572-56-9
1351572-56-9
Chemical Structure
mCPX
- CAS No.: 1351572-56-9
- Formula:C14H19NO3
- Molecular Weight:249.31
InChIKey: ORULNPDGLIIGEX-UHFFFAOYSA-N
SMILES: O=C(C)ON(C(C1CCCCC1)=CC(C)=C2)C2=O
Biological Activity: mCPX is a prodrug of the antifungal agent Ciclopirox olamine (CPX) (HY-B0450A). CPX exhibits bacteriostatic and iron-chelating activities, while mCPX enhances the iron stability of CPX. mCPX inherits the core mechanism pathway of CPX and can induce EBV lytic reactivation in EBV+ gastric cancer cells via the hypoxia pathway (HIF‑1α). mCPX is applicable to research related to EBV-positive gastric cancer[1].
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mCPX | mCPX is a prodrug of the antifungal agent Ciclopirox olamine (CPX) (HY-B0450A). CPX exhibits bacteriostatic and iron-chelating activities, while mCPX enhances the iron stability of CPX. mCPX inherits the core mechanism pathway of CPX and can induce EBV lytic reactivation in EBV+ gastric cancer cells via the hypoxia pathway (HIF‑1α). mCPX is applicable to research related to EBV-positive gastric cancer. | |||||||||||||||||||||
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