1352296-65-1
Chemical Structure
Antifungal agent 173
- CAS No.: 1352296-65-1
- Formula:C23H32ClNO5
- Molecular Weight:437.96
IUPAC Name: (E)-2,6-di-tert-butyl-4-(4-(dimethylamino)styryl)pyrylium perchlorate
InChIKey: VMHHIKFQHFTOTC-RRABGKBLSA-M
SMILES: O=Cl(=O)([O-])=O.CN(C)C(C=C1)=CC=C1/C=C/C2=CC(C(C)(C)C)=[O+]C(C(C)(C)C)=C2
Biological Activity: Antifungal agent 173 is an orally active antifungal (fungal) agent. Antifungal agent 173 disrupts fungal cell membrane integrity, inhibits yeast-hypha transition in Candida species, and suppresses biofilms. Antifungal agent 173 prevents mouse mortality in a mouse model of systemic candidiasis and reduces tongue lesions in a mouse model of oropharyngeal candidiasis. Antifungal agent 173 is applicable to research related to candidiasis[1].
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Antifungal agent 173 | Antifungal agent 173 is an orally active antifungal (fungal) agent. Antifungal agent 173 disrupts fungal cell membrane integrity, inhibits yeast-hypha transition in Candida species, and suppresses biofilms. Antifungal agent 173 prevents mouse mortality in a mouse model of systemic candidiasis and reduces tongue lesions in a mouse model of oropharyngeal candidiasis. Antifungal agent 173 is applicable to research related to candidiasis. | |||||||||||||||||||||
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