135911-02-3
135911-02-3
Chemical Structure
RP 67580
- CAS No.: 135911-02-3
- Formula:C29H30N2O2
- Molecular Weight:438.56
IUPAC Name: (3aR,7aR)-2-(1-imino-2-(2-methoxyphenyl)ethyl)-7,7-diphenyloctahydro-4H-isoindol-4-one
InChIKey: VWBOQFANCXZMAU-LOSJGSFVSA-N
SMILES: O=C1[C@@]2([H])CN(C(CC3=CC=CC=C3OC)=N)C[C@@]2([H])C(C4=CC=CC=C4)(C5=CC=CC=C5)CC1
Biological Activity: RP 67580 is a non-peptide antagonist of substance P (SP), competitively inhibits the binding of [3H]SP to neurokinin receptor 1 (NK1 receptor) in rat brain membranes with a Ki value of 4.16 nM. RP 67580 is a specific antagonist of NK1 receptors and can be used in the research of pain and neurogenic inflammation[1].
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RP 67580 | 97.4% | RP 67580 is a non-peptide antagonist of substance P (SP), competitively inhibits the binding of [3H]SP to neurokinin receptor 1 (NK1 receptor) in rat brain membranes with a Ki value of 4.16 nM. RP 67580 is a specific antagonist of NK1 receptors and can be used in the research of pain and neurogenic inflammation. | ||||||||||||||||||||
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