1360433-93-7
1360433-93-7
Chemical Structure
KW-2450 tosylate
- CAS No.: 1360433-93-7
- Formula:C35H37N5O6S2
- Molecular Weight:687.83
IUPAC Name: (E)-N-(2-(2-(1H-indazol-3-yl)vinyl)-5-((4-(2-hydroxyacetyl)piperazin-1-yl)methyl)phenyl)-3-methylthiophene-2-carboxamide 4-methylbenzenesulfonate
InChIKey: SIJKXSMUXNJNQM-HRNDJLQDSA-N
SMILES: OCC(N(CC1)CCN1CC2=CC(NC(C3=C(C)C=CS3)=O)=C(/C=C/C4=NNC5=C4C=CC=C5)C=C2)=O.CC6=CC=C(S(=O)(O)=O)C=C6
Biological Activity: KW-2450 tosylate is an orally active Aurora A and B kinases, IGF-1R, and IR tyrosine kinases inhibitor. KW-2450 tosylate induces Apoptosis. KW-2450 tosylate also exhibits anticancer activity against triple-negative breast cancer[1].
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KW-2450 tosylate | KW-2450 tosylate is an orally active Aurora A and B kinases, IGF-1R, and IR tyrosine kinases inhibitor. KW-2450 tosylate induces Apoptosis. KW-2450 tosylate also exhibits anticancer activity against triple-negative breast cancer. | |||||||||||||||||||||
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