1360869-92-6
1360869-92-6
Chemical Structure
DLC27-14
- CAS No.: 1360869-92-6
- Formula:C25H25NO4
- Molecular Weight:403.47
IUPAC Name: 3-(2-((4'-(tert-butyl)-[1,1'-biphenyl]-4-yl)oxy)acetamido)benzoic acid
InChIKey: QXBOQILKUMBONF-UHFFFAOYSA-N
SMILES: O=C(C1=CC(NC(COC2=CC=C(C3=CC=C(C(C)(C)C)C=C3)C=C2)=O)=CC=C1)O
Biological Activity: DLC27-14 is a HIV Nef inhibitor with the IC50 of 15.92 μM. DLC27-14 can be used for study of HIV-1[1][2].
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DLC27-14 | DLC27-14 is a HIV Nef inhibitor with the IC50 of 15.92 μM. DLC27-14 can be used for study of HIV-1. | |||||||||||||||||||||
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References
- [1]. Lugari A, et al. A specific protein disorder catalyzer of HIV-1 Nef. Bioorg Med Chem. 2011;19(24):7401-7406. [Content Brief]
- [2]. Trible RP, et al. Discovery of a diaminoquinoxaline benzenesulfonamide antagonist of HIV-1 Nef function using a yeast-based phenotypic screen. Retrovirology. 2013;10:135. Published 2013 Nov 14. [Content Brief]
