136087-29-1
Chemical Structure
Isomucronulatol 7-O-glucoside
Synonym(s): Isomucronulatol 7-O-β-glucoside
- CAS No.: 136087-29-1
- Formula:C23H28O10
- Molecular Weight:464.46
IUPAC Name: (2S,3R,4S,5S,6R)-2-(((R)-3-(2-hydroxy-3,4-dimethoxyphenyl)chroman-7-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
InChIKey: SXHOGLPTLQBGDO-ZVSSUSCDSA-N
SMILES: OC1=C([C@H]2CC3=CC=C(O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)CO)C=C3OC2)C=CC(OC)=C1OC
Biological Activity: Isomucronulatol 7-O-glucoside (Isomucronulatol 7-O-β-D-glucoside) is an isoflavonoid glycoside isolated from the roots of Astragalus membranaceus. Isomucronulatol 7-O-glucoside targets inflammation-related pathways in vitro to exert anti-inflammatory activity without cytotoxicity at effective concentrations. Isomucucronulatol 7-O-glucoside inhibits NO production and weakly suppresses IL‑12 p40 production in vitro. Isomucronulatol 7-O-glucoside can be used for the research on inflammation[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Isomucronulatol 7-O-glucoside | 99.40% | Isomucronulatol 7-O-glucoside (Isomucronulatol 7-O-β-D-glucoside) is an isoflavonoid glycoside isolated from the roots of Astragalus membranaceus. Isomucronulatol 7-O-glucoside targets inflammation-related pathways in vitro to exert anti-inflammatory activity without cytotoxicity at effective concentrations. Isomucucronulatol 7-O-glucoside inhibits NO production and weakly suppresses IL‑12 p40 production in vitro. Isomucronulatol 7-O-glucoside can be used for the research on inflammation. | ||||||||||||||||||||
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References
- [1]. Li W, et al. Flavonoids from Astragalus membranaceus and their inhibitory effects on LPS-stimulated pro-inflammatory cytokine production in bone marrow-derived dendritic cells. Arch Pharm Res. 2014;37(2):186-192. [Content Brief]
- [2]. Zhang LJ, et al. New isoflavonoid glycosides and related constituents from Astragali Radix (Astragalus membranaceus) and their inhibitory activity on nitric oxide production. J Agric Food Chem. 2011 Feb 23;59(4):1131-1137.
