13640-26-1
13640-26-1
Chemical Structure
Pimprinine
- CAS No.: 13640-26-1
- Formula:C12H10N2O
- Molecular Weight:198.22
IUPAC Name: 5-(1H-indol-3-yl)-2-methyloxazole
InChIKey: WZJPGCHCOHYLMB-UHFFFAOYSA-N
SMILES: CC1=NC=C(C2=CNC3=C2C=CC=C3)O1
Biological Activity: Pimprinine is a potent monoamine oxidase inhibitor, could be isolated from fermented broths. Pimprinine has antioxidative activity and anticonvulsant activity. Pimprinine inhibits tremorine-induced tremors and analgesia in mice[1][2][3].
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Pimprinine | Pimprinine is a potent monoamine oxidase inhibitor, could be isolated from fermented broths. Pimprinine has antioxidative activity and anticonvulsant activity. Pimprinine inhibits tremorine-induced tremors and analgesia in mice. | |||||||||||||||||||||
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References
- [1]. Takeuchi T, et, al. Monoamine oxidase inhibitors isolated from fermented broths. J Antibiot (Tokyo). 1973 Mar;26(3):162-7. [Content Brief]
- [2]. Miao YP, et, al. Synthesis and antioxidative activity of 2-substituted phenyl-5-(3'-indolyl)-oxazole derivatives. Yao Xue Xue Bao. 2004 Jan;39(1):37-40. [Content Brief]
- [3]. Naik SR, et, al. Pimprinine, an extracellular alkaloid produced by Streptomyces CDRIL-312: fermentation, isolation and pharmacological activity. J Biotechnol. 2001 Jun 1;88(1):1-10. [Content Brief]
