1364123-68-1
1364123-68-1
Chemical Structure
(R)-(+)-O-Demethylbuchenavianine
- CAS No.: 1364123-68-1
- Formula:C21H21NO4
- Molecular Weight:351.40
InChIKey: BBZGOLNDVQZCIH-CQSZACIVSA-N
SMILES: OC1=CC(O)=C(C(C=C(C2=CC=CC=C2)O3)=O)C3=C1[C@@H]4N(CCCC4)C
Biological Activity: (R)-(+)-O-Demethylbuchenavianine is an inhibitor for Cyclin-dependent kinases (CDK). (R)-(+)-O-Demethylbuchenavianine inhibits CDK1, CDK5, glycogen synthase kinase-3 (GSK3), cdc2-like kinase (CLK1) and dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A), with IC50s of 1.1, 0.95, >10, >10 and >10 μM, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(R)-(+)-O-Demethylbuchenavianine | 98.67% | (R)-(+)-O-Demethylbuchenavianine is an inhibitor for Cyclin-dependent kinases (CDK). (R)-(+)-O-Demethylbuchenavianine inhibits CDK1, CDK5, glycogen synthase kinase-3 (GSK3), cdc2-like kinase (CLK1) and dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A), with IC50s of 1.1, 0.95, >10, >10 and >10 μM, respectively. | ||||||||||||||||||||
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