136623-01-3
136623-01-3
Chemical Structure
NS-102
- CAS No.: 136623-01-3
- Formula:C12H11N3O4
- Molecular Weight:261.23
IUPAC Name: (Z)-3-(hydroxyimino)-5-nitro-1,3,6,7,8,9-hexahydro-2H-benzo[g]indol-2-one
InChIKey: SCDBMLHUXJBJSS-UHFFFAOYSA-N
SMILES: O=C1NC2=C(C=C([N+]([O-])=O)C3=C2CCCC3)/C1=N/O
Biological Activity: NS-102 is a selective kainate (GluK2) receptor antagonist. NS-102 is a potent GluR6/7 receptor antagonist[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NS-102 | 99.01% | NS-102 is a selective kainate (GluK2) receptor antagonist. NS-102 is a potent GluR6/7 receptor antagonist. | ||||||||||||||||||||
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References
- [1]. Selva Baltan Tekkök, et al. Excitotoxic mechanisms of ischemic injury in myelinated white matter. J Cereb Blood Flow Metab. 2007 Sep;27(9):1540-52. [Content Brief]
- [2]. P Liang, et al. Sevoflurane activates hippocampal CA3 kainate receptors (Gluk2) to induce hyperactivity during induction and recovery in a mouse model. Br J Anaesth. 2017 Nov 1;119(5):1047-1054. [Content Brief]
- [3]. Barbara Gisabella, et al. Kainate receptor-mediated modulation of hippocampal fast spiking interneurons in a rat model of schizophrenia. PLoS One. 2012;7(3):e32483. [Content Brief]
