1372642-77-7
Chemical Structure
KMG-301AM
- CAS No.: 1372642-77-7
- Formula:C30H28N3O6+
- Molecular Weight:526.56
IUPAC Name: N-(9-(3-((acetoxymethoxy)carbonyl)-4-oxo-4H-quinolizin-1-yl)-6-(dimethylamino)-3H-xanthen-3-ylidene)-N-methylmethanaminium
InChIKey: JNVNRNBXFHGZHT-UHFFFAOYSA-N
SMILES: O=C1C(C(OCOC(C)=O)=O)=CC(C(C2=CC=C(N(C)C)C=C2O3)=C4C3=C/C(C=C4)=[N+](C)/C)=C5C=CC=CN51
Biological Activity: KMG-301AM is the acetoxy methyl esterified form of KMG-301. KMG-301AM successfully accumulates in mitochondria and then it is hydrolyzed to KMG-301. KMG-301 is an Mg2+-selective fluorescent probe functional in mitochondria in intact cells. Since the mitochondrial membrane is impermeable to KMG-301, it is not released upon depolarization of the mitochondrial membrane potential. KMG-301 can indicate changes in mitochondrial Mg2+ concentration and shows Mg2+ transport across the mitochondrial membrane in the early phases of a cellular model[1].
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KMG-301AM | KMG-301AM is the acetoxy methyl esterified form of KMG-301. KMG-301AM successfully accumulates in mitochondria and then it is hydrolyzed to KMG-301. KMG-301 is an Mg2+-selective fluorescent probe functional in mitochondria in intact cells. Since the mitochondrial membrane is impermeable to KMG-301, it is not released upon depolarization of the mitochondrial membrane potential. KMG-301 can indicate changes in mitochondrial Mg2+ concentration and shows Mg2+ transport across the mitochondrial membrane in the early phases of a cellular model. | |||||||||||||||||||||
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