1373422-53-7
1373422-53-7
Chemical Structure
GSK-J1
- CAS No.: 1373422-53-7
- Formula:C22H23N5O2
- Molecular Weight:389.45
IUPAC Name: 3-((2-(pyridin-2-yl)-6-(1,2,4,5-tetrahydro-3H-benzo[d]azepin-3-yl)pyrimidin-4-yl)amino)propanoic acid
InChIKey: AVZCPICCWKMZDT-UHFFFAOYSA-N
SMILES: OC(CCNC1=NC(C2=NC=CC=C2)=NC(N(CC3)CCC4=C3C=CC=C4)=C1)=O
Biological Activity: GSK-J1, a chemical probe, is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with IC50 of 60 nM towards KDM6B.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
GSK-J1 | 99.79% | GSK-J1, a chemical probe, is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with IC50 of 60 nM towards KDM6B. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
