1374663-29-2
1374663-29-2
Chemical Structure
Sulfo-ara-F-NMN
Synonym(s): CZ-48
- CAS No.: 1374663-29-2
- Formula:C11H14FN2O6PS
- Molecular Weight:352.28
IUPAC Name: O-(((2R,3R,4S,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-4-fluoro-3-hydroxytetrahydrofuran-2-yl)methyl) O-hydrogen phosphorothioate
InChIKey: SIQYQBAPGWSZQF-PKIKSRDPSA-N
SMILES: O=C(N)C1=CC=C[N+]([C@@H]2O[C@H](COP([O-])(O)=S)[C@@H](O)[C@@H]2F)=C1
Biological Activity: Sulfo-ara-F-NMN (CZ-48) is a mimetic of nicotinamide mononucleotide (NMN). Sulfo-ara-F-NMN acts selectively, activating SARM1 but inhibiting CD38 (IC50 around 10 μM). Sulfo-ara-F-NMN induces intracellular cyclic ADP-ribose (cADPR) production[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Sulfo-ara-F-NMN | 99.18% | Sulfo-ara-F-NMN (CZ-48) is a mimetic of nicotinamide mononucleotide (NMN). Sulfo-ara-F-NMN acts selectively, activating SARM1 but inhibiting CD38 (IC50 around 10 μM). Sulfo-ara-F-NMN induces intracellular cyclic ADP-ribose (cADPR) production. | ||||||||||||||||||||
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