1376162-36-5
1376162-36-5
Chemical Structure
C1s-IN-1 trihydrochloride
- CAS No.: 1376162-36-5
- Formula:C16H22Cl3N5
- Molecular Weight:390.74
IUPAC Name: 6-(4-phenylpiperazin-1-yl)nicotinimidamide trihydrochloride
InChIKey: URSINTNKQBZAQT-UHFFFAOYSA-N
SMILES: N=C(C1=CN=C(N2CCN(CC2)C3=CC=CC=C3)C=C1)N.Cl.Cl.Cl
Biological Activity: C1s-IN-1 trihydrochloride (Compound A1) is the selective inhibitor for C1s protease with the Ki of 5.8 μM. C1s-IN-1 trihydrochloride inhibits cleavage of C2 by C1s with an IC50 of 85 μM, inhibits the activation of classic pathway with an IC50 of 22 μM. C1s-IN-1 trihydrochloride is the competitive inhibitor for thrombin with the Ki of 51.2 μM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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C1s-IN-1 trihydrochloride | 99.73% | C1s-IN-1 trihydrochloride (Compound A1) is the selective inhibitor for C1s protease with the Ki of 5.8 μM. C1s-IN-1 trihydrochloride inhibits cleavage of C2 by C1s with an IC50 of 85 μM, inhibits the activation of classic pathway with an IC50 of 22 μM. C1s-IN-1 trihydrochloride is the competitive inhibitor for thrombin with the Ki of 51.2 μM. | ||||||||||||||||||||
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