1377338-26-5
Chemical Structure
Jasplakinolide probe-1
- CAS No.: 1377338-26-5
- Formula:C43H59N5O8
- Molecular Weight:773.96
InChIKey: GHQGDYJCGTYZHS-OHQCFJSQSA-N
SMILES: O=C(N[C@@H](C1=CC=C(C=C1)O)CC(O[C@H](CC/C=C(C[C@@H](C(N[C@H](C(N2C)=O)CCCCNC(OC(C)(C)C)=O)=O)C)\C)C)=O)[C@H]2CC3=CNC4=CC=CC=C34
Biological Activity: Jasplakinolide probe-1 (Compound 12), a Jasplakinolide (HY-P0027) derivative, is a Jasplakinolide probe. Jasplakinolide probe-1 shows anti-proliferative activity and can inhibit the dynamics of actin, cause the collapse of cell lamellipodia, interfering with the dynamic balance of actin. Jasplakinolide probe-1 can be used for imaging of actin structure in cells conjugated with a fluorescent dye [1].
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Jasplakinolide probe-1 | Jasplakinolide probe-1 (Compound 12), a Jasplakinolide (HY-P0027) derivative, is a Jasplakinolide probe. Jasplakinolide probe-1 shows anti-proliferative activity and can inhibit the dynamics of actin, cause the collapse of cell lamellipodia, interfering with the dynamic balance of actin. Jasplakinolide probe-1 can be used for imaging of actin structure in cells conjugated with a fluorescent dye . | |||||||||||||||||||||
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