137888-11-0
Chemical Structure
Carmoterol hydrochloride
- CAS No.: 137888-11-0
- Formula:C21H25ClN2O4
- Molecular Weight:404.89
IUPAC Name: 8-hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)quinolin-2(1H)-one hydrochloride
InChIKey: SYCWERNQGSKYAG-QVRIGTRMSA-N
SMILES: O=C1NC2=C(C([C@@H](O)CN[C@H](C)CC3=CC=C(OC)C=C3)=CC=C2O)C=C1.Cl
Biological Activity: Carmoterol hydrochloride is a highly potent, selective and long-acting β2-adrenoceptor agonist with the pEC50 of 10.19. Carmoterol has 53 times higher affinity for the β2-adrenoceptors than for the β1-adrenoceptors. Carmoterol hydrochloride can be used for the research of asthma and chronic obstructive pulmonary disease (COPD)[1][2].
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Carmoterol hydrochloride | 98.73% | Carmoterol hydrochloride is a highly potent, selective and long-acting β2-adrenoceptor agonist with the pEC50 of 10.19. Carmoterol has 53 times higher affinity for the β2-adrenoceptors than for the β1-adrenoceptors. Carmoterol hydrochloride can be used for the research of asthma and chronic obstructive pulmonary disease (COPD). | ||||||||||||||||||||
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References
- [1]. Mario Cazzola, et al. β(2) -adrenoceptor agonists: current and future direction. Br J Pharmacol. 2011 May;163(1):4-17. [Content Brief]
- [2]. Giuseppe Rossoni, et al. Positive interaction of the novel beta2-agonist carmoterol and tiotropium bromide in the control of airway changes induced by different challenges in guinea-pigs. Pulm Pharmacol Ther. 2007;20(3):250-7. [Content Brief]
