137888-49-4
137888-49-4
Chemical Structure
CGP 20712
- CAS No.: 137888-49-4
- Formula:C23H25F3N4O5
- Molecular Weight:494.46
IUPAC Name: 2-hydroxy-5-(2-((2-hydroxy-3-(4-(1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl)phenoxy)propyl)amino)ethoxy)benzamide
InChIKey: GKJZEKSHCJELPL-UHFFFAOYSA-N
SMILES: O=C(N)C1=CC(OCCNCC(O)COC2=CC=C(C3=NC(C(F)(F)F)=CN3C)C=C2)=CC=C1O
Biological Activity: CGP 20712 is a highly selective β1-adrenoceptor antagonist (Ki=0.3 nmol/L). CGP 20712’s primary mechanism of action is through competitively binding to β1-receptors, thereby blocking the positive chronotropic effects of adrenaline and noradrenaline[1].
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CGP 20712 | CGP 20712 is a highly selective β1-adrenoceptor antagonist (Ki=0.3 nmol/L). CGP 20712’s primary mechanism of action is through competitively binding to β1-receptors, thereby blocking the positive chronotropic effects of adrenaline and noradrenaline. | |||||||||||||||||||||
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