1380088-01-6
1380088-01-6
Chemical Structure
c-Src Kinase-IN-1
- CAS No.: 1380088-01-6
- Formula:C32H23ClN8
- Molecular Weight:555.03
InChIKey: HOORJISMCJYQLV-UHFFFAOYSA-N
SMILES: NC1=C(C(C2=CC=C(Cl)C=C2)=NN3C4=CC(C5=CN=NN5CC6=CC=C(C7=CC=CC=C7)C=C6)=CC=C4)C3=NC=N1
Biological Activity: c-Src Kinase-IN-1 is a highly selective, cell-permeable inhibitor of c-Src kinase that suppresses cancer cell growth. c-Src Kinase-IN-1 has a Ki of 44 nM and a Kd value of 86 nM against chicken-derived c-Src. c-Src Kinase-IN-1 interacts with the phosphate-binding loop of c-Src and exhibits selectivity toward homologous Src family kinases and c-Abl. c-Src Kinase-IN-1 can be used in cancer-related research[1].
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c-Src Kinase-IN-1 | c-Src Kinase-IN-1 is a highly selective, cell-permeable inhibitor of c-Src kinase that suppresses cancer cell growth. c-Src Kinase-IN-1 has a Ki of 44 nM and a Kd value of 86 nM against chicken-derived c-Src. c-Src Kinase-IN-1 interacts with the phosphate-binding loop of c-Src and exhibits selectivity toward homologous Src family kinases and c-Abl. c-Src Kinase-IN-1 can be used in cancer-related research. | |||||||||||||||||||||
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