1380288-87-8
1380288-87-8
Chemical Structure
Pinometostat
Synonym(s): EPZ-5676
- CAS No.: 1380288-87-8
- Formula:C30H42N8O3
- Molecular Weight:562.71
IUPAC Name: (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-((((1r,3S)-3-(2-(5-(tert-butyl)-1H-benzo[d]imidazol-2-yl)ethyl)cyclobutyl)(isopropyl)amino)methyl)tetrahydrofuran-3,4-diol
InChIKey: LXFOLMYKSYSZQS-LURJZOHASA-N
SMILES: NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](CN([C@@H]4C[C@H](CCC5=NC6=C(C=CC(C(C)(C)C)=C6)N5)C4)C(C)C)O3
Biological Activity: Pinometostat (EPZ-5676) is a potent DOT1L histone methyltransferase inhibitor with a Ki of 80 pM.
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Pinometostat | 99.94% | Pinometostat (EPZ-5676) is a potent DOT1L histone methyltransferase inhibitor with a Ki of 80 pM. | ||||||||||||||||||||
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Pinometostat (Standard) | ≥98% | Pinometostat (Standard) is the analytical standard of Pinometostat. This product is intended for research and analytical applications. Pinometostat (EPZ-5676) is a potent DOT1L histone methyltransferase inhibitor with a Ki of 80 pM. | ||||||||||||||||||||
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