1386455-51-1
Chemical Structure
Factor D inhibitor 6
- CAS No.: 1386455-51-1
- Formula:C23H22ClFN6O3
- Molecular Weight:484.91
IUPAC Name: 1-(2-((1R,3S,5R)-3-(((R)-1-(3-chloro-2-fluorophenyl)ethyl)carbamoyl)-2-azabicyclo[3.1.0]hexan-2-yl)-2-oxoethyl)-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
InChIKey: YAALCKJNOOFODD-SKNMWMDOSA-N
SMILES: O=C([C@H]1N(C(CN2N=C(C(N)=O)C3=C2C=NC=C3)=O)[C@]4([H])C[C@]4([H])C1)N[C@@H](C5=CC=CC(Cl)=C5F)C
Biological Activity: Factor D inhibitor 6 is a potent, highly selective and orally active factor D (FD) inhibitor with an IC50 of 30 nM and a Kd of 6 nM. Factor D inhibitor 6 is inactive against factor B, lassical and lectin complement-pathway activation, and a broad assay panel of receptors, ion channels, kinases and proteases[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Factor D inhibitor 6 | 99.18% | Factor D inhibitor 6 is a potent, highly selective and orally active factor D (FD) inhibitor with an IC50 of 30 nM and a Kd of 6 nM. Factor D inhibitor 6 is inactive against factor B, lassical and lectin complement-pathway activation, and a broad assay panel of receptors, ion channels, kinases and proteases. | ||||||||||||||||||||
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