1390616-76-8
1390616-76-8
Chemical Structure
Aldose reductase-IN-3
- CAS No.: 1390616-76-8
- Formula:C18H12ClN3O2S2
- Molecular Weight:401.89
IUPAC Name: (Z)-5-(4-chlorobenzylidene)-2-((6-methoxybenzo[d]thiazol-2-yl)amino)thiazol-4(5H)-one
InChIKey: VXOAIZOEANHDCR-NVNXTCNLSA-N
SMILES: O=C1N=C(NC2=NC3=CC=C(OC)C=C3S2)S/C1=C\C4=CC=C(Cl)C=C4
Biological Activity: Aldose reductase-IN-3 (Compound 5) is a potent and moderately selective inhibitor of aldose reductase (AR) with an IC50 of 3.99 μM. Aldose reductase has recently emerged as a molecular target that is involved in various inflammatory diseases, including sepsis. Aldose reductase-IN-3 has the potential for the research of sepsis[1].
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Aldose reductase-IN-3 | Aldose reductase-IN-3 (Compound 5) is a potent and moderately selective inhibitor of aldose reductase (AR) with an IC50 of 3.99 μM. Aldose reductase has recently emerged as a molecular target that is involved in various inflammatory diseases, including sepsis. Aldose reductase-IN-3 has the potential for the research of sepsis. | |||||||||||||||||||||
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