139143-28-5
139143-28-5
Chemical Structure
HLA-B*0801-binding EBV peptide
- CAS No.: 139143-28-5
- Formula:C49H77N15O11
- Molecular Weight:1052.23
InChIKey: BVTUEQNHVTVWSF-AVTNSMPVSA-N
SMILES: O=C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CC1=CC=C(C=C1)O)C(NCC(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC2=CC=CC=C2)N
Biological Activity: HLA-B*0801-binding EBV peptide is an Epstein-Barr virus (EBV) epitope FLRGRAYGL. HLA-B*0801-binding EBV peptide can bind to the HLA-B*0801 molecule. HLA-B*0801-binding EBV peptide can be presented to CD8+ T cells through HLA-B*0801 to activate a specific immune response[1][2].
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HLA-B*0801-binding EBV peptide | HLA-B*0801-binding EBV peptide is an Epstein-Barr virus (EBV) epitope FLRGRAYGL. HLA-B*0801-binding EBV peptide can bind to the HLA-B*0801 molecule. HLA-B*0801-binding EBV peptide can be presented to CD8+ T cells through HLA-B*0801 to activate a specific immune response. | |||||||||||||||||||||
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References
- [1]. Ely LK, et al. Antagonism of antiviral and allogeneic activity of a human public CTL clonotype by a single altered peptide ligand: implications for allograft rejection. J Immunol. 2005 May 1;174(9):5593-601. [Content Brief]
- [2]. Burrows SR, et al. T cell receptor repertoire for a viral epitope in humans is diversified by tolerance to a background major histocompatibility complex antigen. J Exp Med. 1995 Dec 1;182(6):1703-15. [Content Brief]
