1392224-59-7
Chemical Structure
MyomiRs-IN-1
- CAS No.: 1392224-59-7
- Formula:C33H27NO6
- Molecular Weight:533.57
IUPAC Name: tert-butyl (5-(8a-methoxy-3,8-dioxo-2-phenyl-2a,3,8,8a-tetrahydrocyclobuta[b]naphthalen-1-yl)quinolin-8-yl) carbonate
InChIKey: GNUJEUMWYJVRKO-UHFFFAOYSA-N
SMILES: O=C(OC1=C2N=CC=CC2=C(C3=C(C4=CC=CC=C4)C(C3(OC)C(C5=C6C=CC=C5)=O)C6=O)C=C1)OC(C)(C)C
Biological Activity: MyomiRs-IN-1 is a myomiRs inhibitor with activity to inhibit myoD translation in C2C12 cells. MyomiRs-IN-1 does not change the expression level of myoD mRNA, while downregulating the expression of differentiation markers. MyomiRs-IN-1 affects the expression of myomiRs in muscle cells by regulating the regulatory pathway between miR-221/222 and myoD. The application of MyomiRs-IN-1 can facilitate research on muscle development and related diseases[1].
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MyomiRs-IN-1 | MyomiRs-IN-1 is a myomiRs inhibitor with activity to inhibit myoD translation in C2C12 cells. MyomiRs-IN-1 does not change the expression level of myoD mRNA, while downregulating the expression of differentiation markers. MyomiRs-IN-1 affects the expression of myomiRs in muscle cells by regulating the regulatory pathway between miR-221/222 and myoD. The application of MyomiRs-IN-1 can facilitate research on muscle development and related diseases. | |||||||||||||||||||||
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