13929-35-6
Chemical Structure
Rifamycin B
Synonym(s): 4-O-(Carboxymethyl)-Rifamycin
- CAS No.: 13929-35-6
- Formula:C39H49NO14
- Molecular Weight:755.80
InChIKey: SQTCRTQCPJICLD-KTQDUKAHSA-N
SMILES: C/C(C(N1)=O)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]([C@@H](OC)/C=C/O[C@]2(C)C(C3=C(O2)C(C)=C(O)C4=C3C(OCC(O)=O)=CC1=C4O)=O)C
Biological Activity: Rifamycin B (4-O-(Carboxymethyl)-Rifamycin) is a member of ansamycin antibiotics family with an anti-mycobacterial activity against tuberculosis, leprosy and AIDS-related mycobacterial infections. Rifamycin B is a metabolic product of Nocardia inediterranei, which can yield Rifamycin O and Rifamycin S (HY-125365) by microbial transformation[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Rifamycin B | 95.0% | Rifamycin B (4-O-(Carboxymethyl)-Rifamycin) is a member of ansamycin antibiotics family with an anti-mycobacterial activity against tuberculosis, leprosy and AIDS-related mycobacterial infections. Rifamycin B is a metabolic product of Nocardia inediterranei, which can yield Rifamycin O and Rifamycin S (HY-125365) by microbial transformation. | ||||||||||||||||||||
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References
- [1]. Seong BL, et al. Microbial transformation of rifamycin B: a new synthetic approach to rifamycin derivatives. J Antibiot (Tokyo). 1983 Oct;36(10):1402-4. [Content Brief]
- [2]. Jin ZH, et al. Scale-up of rifamycin B fermentation with Amycolatoposis mediterranei. J Zhejiang Univ Sci. 2004 Dec;5(12):1590-6. [Content Brief]
