139290-65-6
139290-65-6
Chemical Structure
Volinanserin
Synonym(s): MDL100907; M 100907
- CAS No.: 139290-65-6
- Formula:C22H28FNO3
- Molecular Weight:373.46
IUPAC Name: (R)-(2,3-dimethoxyphenyl)(1-(4-fluorophenethyl)piperidin-4-yl)methanol
InChIKey: HXTGXYRHXAGCFP-OAQYLSRUSA-N
SMILES: FC1=CC=C(CCN2CCC([C@@]([H])(O)C3=CC=CC(OC)=C3OC)CC2)C=C1
Biological Activity: Volinanserin is a potent and selective antagonist of 5-HT2 receptor, with a Ki of 0.36 nM, and shows 300-fold selectivity for 5-HT2 receptor over 5-HT1c, alpha-1 and DA D2 receptors. Volinanserin has antipsychotic activity.
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Volinanserin | 99.62% | Volinanserin is a potent and selective antagonist of 5-HT2 receptor, with a Ki of 0.36 nM, and shows 300-fold selectivity for 5-HT2 receptor over 5-HT1c, alpha-1 and DA D2 receptors. Volinanserin has antipsychotic activity. | ||||||||||||||||||||
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Volinanserin-d4 hydrochloride | 98.60% | Volinanserin-d4 (hydrochloride) is the deuterium labeled Volinanserin hydrochlorid. Volinanserin is a potent and selective antagonist of 5-HT2 receptor, with a Ki of 0.36 nM, and shows 300-fold selectivity for 5-HT2 receptor over 5-HT1c, alpha-1 and DA D2 receptors. Volinanserin has antipsychotic activity. | ||||||||||||||||||||
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