139339-02-9
Chemical Structure
KF-17625
- CAS No.: 139339-02-9
- Formula:C15H10N4O
- Molecular Weight:262.27
IUPAC Name: 5-phenyl-1,5-dihydro-4H-imidazo[4,5-c][1,8]naphthyridin-4-one
InChIKey: NDDBRRFHXNPOLY-UHFFFAOYSA-N
SMILES: O=C1C2=C(C3=C(N1C4=CC=CC=C4)N=CC=C3)NC=N2
Biological Activity: KF-17625 is an orally active bronchodilator. KF-17625 can inhibit bronchoconstriction induced by Carbachol (HY-B1208), Histamine (HY-B1204), or Leukotriene D4 (HY-113456). KF-17625 can inhibit canine tracheal phosphodiesterase (PDE) IV (IC50 = 12 μM) and Concanavalin-A (HY-P2149)-induced histamine release from rat mast cells (44% inhibition at 10 mM). KF-17625 can be used for the researches of immunology and inflammation[1].
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KF-17625 | KF-17625 is an orally active bronchodilator. KF-17625 can inhibit bronchoconstriction induced by Carbachol (HY-B1208), Histamine (HY-B1204), or Leukotriene D4 (HY-113456). KF-17625 can inhibit canine tracheal phosphodiesterase (PDE) IV (IC50 = 12 μM) and Concanavalin-A (HY-P2149)-induced histamine release from rat mast cells (44% inhibition at 10 mM). KF-17625 can be used for the researches of immunology and inflammation. | |||||||||||||||||||||
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