139340-56-0
139340-56-0
Chemical Structure
Darbufelone mesylate
Synonym(s): CI-1004 mesylate
- CAS No.: 139340-56-0
- Formula:C19H28N2O5S2
- Molecular Weight:428.57
IUPAC Name: (Z)-2-amino-5-(3,5-di-tert-butyl-4-hydroxybenzylidene)thiazol-4(5H)-one methanesulfonate
InChIKey: BAZGFSKJAVQJJI-CHHCPSLASA-N
SMILES: O=C1N=C(N)S/C1=C\C2=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C2.CS(=O)(O)=O
Biological Activity: Darbufelone mesylate (CI-1004 mesylate) is a dual inhibitor of cellular PGF2α and LTB4 production. Darbufelone potently inhibits PGHS-2 (IC50 = 0.19 μM) but is much less potent with PGHS-1 (IC50= 20 μM).
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Darbufelone mesylate | 99.65% | Darbufelone mesylate (CI-1004 mesylate) is a dual inhibitor of cellular PGF2α and LTB4 production. Darbufelone potently inhibits PGHS-2 (IC50 = 0.19 μM) but is much less potent with PGHS-1 (IC50= 20 μM). | ||||||||||||||||||||
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Darbufelone mesylate (Standard) | ≥98% | Darbufelone (mesylate) (Standard) is the analytical standard of Darbufelone (mesylate) (HY-101438A). This product is intended for research and analytical applications. Darbufelone mesylate (CI-1004 mesylate) is a dual inhibitor of cellular PGF2α and LTB4 production. Darbufelone potently inhibits PGHS-2 (IC50 = 0.19 μM) but is much less potent with PGHS-1 (IC50= 20 μM). | ||||||||||||||||||||
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