1395061-03-6
Chemical Structure
Bis-(IAA-piperazinyl) sulforhodamine
- CAS No.: 1395061-03-6
- Formula:C31H30I2N4O6S
- Molecular Weight:840.47
IUPAC Name: 1,1'-((1,1-dioxidospiro[benzo[c][1,2]oxathiole-3,9'-xanthene]-3',6'-diyl)bis(piperazine-4,1-diyl))bis(2-iodoethan-1-one)
InChIKey: VTJYWHGYIPKGNU-UHFFFAOYSA-N
SMILES: O=C(N1CCN(C2=CC=C3C(OC4=CC(=CC=C4C53OS(=O)(=O)C=6C=CC=CC65)N7CCN(C(=O)CI)CC7)=C2)CC1)CI
Biological Activity: Bis-(IAA-piperazinyl) sulforhodamine is a bifunctional thiol-reactive sulforhodamine derivative. Bis-(IAA-piperazinyl) sulforhodamine covalently labels cysteine thiols via iodoacetyl groups, including cysteine residues at the helical protrusion tips of archaeal chaperonins. Bis-(IAA-piperazinyl) sulforhodamine can be used to investigate the rotation mechanism of chaperonin helical protrusions[1].
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Bis-(IAA-piperazinyl) sulforhodamine | Bis-(IAA-piperazinyl) sulforhodamine is a bifunctional thiol-reactive sulforhodamine derivative. Bis-(IAA-piperazinyl) sulforhodamine covalently labels cysteine thiols via iodoacetyl groups, including cysteine residues at the helical protrusion tips of archaeal chaperonins. Bis-(IAA-piperazinyl) sulforhodamine can be used to investigate the rotation mechanism of chaperonin helical protrusions. | |||||||||||||||||||||
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