1400876-94-9
1400876-94-9
Chemical Structure
JAK-IN-3
- CAS No.: 1400876-94-9
- Formula:C18H20N4O3
- Molecular Weight:340.38
IUPAC Name: 4-(((2R,3R)-1,3-dihydroxybutan-2-yl)amino)-6-phenylpyrrolo[1,2-b]pyridazine-3-carboxamide
InChIKey: PRWQQLFMBINSAW-IAQYHMDHSA-N
SMILES: O=C(C1=C(N[C@@H]([C@H](O)C)CO)C2=CC(C3=CC=CC=C3)=CN2N=C1)N
Biological Activity: JAK-IN-3 (compound 22) is a potent JAK inhibitor, with IC50 values of 3 nM, 5 nM, 34 nM and 70 nM for JAK3, JAK1, TYK2 and JAK2, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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JAK-IN-3 | 98.92% | JAK-IN-3 (compound 22) is a potent JAK inhibitor, with IC50 values of 3 nM, 5 nM, 34 nM and 70 nM for JAK3, JAK1, TYK2 and JAK2, respectively. | ||||||||||||||||||||
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JAK-IN-3 (Standard) | ≥98% | JAK-IN-3 (Standard) is the analytical standard of JAK-IN-3 (HY-111750). This product is intended for research and analytical applications. JAK-IN-3 (compound 22) is a potent JAK inhibitor, with IC50 values of 3 nM, 5 nM, 34 nM and 70 nM for JAK3, JAK1, TYK2 and JAK2, respectively. | ||||||||||||||||||||
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