1400998-20-0
Chemical Structure
Pz 285
- CAS No.: 1400998-20-0
- Formula:C42H50N8O16
- Molecular Weight:922.89
InChIKey: QYOMZRNTAXOQRM-GIEDQAFWSA-N
SMILES: C[C@@]1(OC)OC2=C(/N=C3C(O[C@@](C)(OC)[C@](C)(OC)O4)=C4C(/N=C5C(O[C@@](C)(OC)[C@](C)(OC)O6)=C6/C(N/5)=N/7)=N/3)NC(/N=C8N=C7C9=C\8C(OCCO)=CC=C9OCCO)=C2O[C@@]1(C)OC
Biological Activity: Pz 285 is an anti-cancer agent. Pz 285 shows significant inhibitory effect on the viability of MDA-MB-231 breast cancer cells, with an IC50 of 15.0 μM. Pz 285 exhibits remarkable antitumor effects in the mouse tumor xenograft model constructed with highly lung-metastatic MDA-MB-231 LM24 Her2+ breast cancer cells. Pz 285 can be used for the study of breast cancer, especially metastatic breast cancer[1].
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Pz 285 | Pz 285 is an anti-cancer agent. Pz 285 shows significant inhibitory effect on the viability of MDA-MB-231 breast cancer cells, with an IC50 of 15.0 μM. Pz 285 exhibits remarkable antitumor effects in the mouse tumor xenograft model constructed with highly lung-metastatic MDA-MB-231 LM24 Her2+ breast cancer cells. Pz 285 can be used for the study of breast cancer, especially metastatic breast cancer. | |||||||||||||||||||||
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