1404231-34-0
1404231-34-0
Chemical Structure
ON 146040
- CAS No.: 1404231-34-0
- Formula:C24H23N7O3S
- Molecular Weight:489.55
IUPAC Name: (Z)-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)-7-(4-nitrobenzylidene)-5H-pyrimido[4,5-b][1,4]thiazin-6(7H)-one
InChIKey: PKCHFYZACODWAI-STZFKDTASA-N
SMILES: CN(CC1)CCN1C(C=C2)=CC=C2NC3=NC(S/C(C(N4)=O)=C\C5=CC=C([N+]([O-])=O)C=C5)=C4C=N3
Biological Activity: ON 146040 is a potent PI3Kα and PI3Kδ (IC50≈14 and 20 nM, respectively) inhibitor. ON 146040 also inhibits Abl1 (IC50<150 nM).
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ON 146040 | 95.05% | ON 146040 is a potent PI3Kα and PI3Kδ (IC50≈14 and 20 nM, respectively) inhibitor. ON 146040 also inhibits Abl1 (IC50<150 nM). | ||||||||||||||||||||
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