1407523-31-2
Chemical Structure
Fl-DIBO
- CAS No.: 1407523-31-2
- Formula:C19H12O3
- Molecular Weight:288.30
IUPAC Name: (8S,11S)-8-((1H-imidazol-5-yl)methyl)-N-((S)-6-ethanethioamido-1-(((10S,13S)-10-(2-(methylthio)ethyl)-9,12-dioxo-2-oxa-8,11-diaza-1(1,4)-benzenacyclotetradecaphane-13-yl)amino)-1-oxohexan-2-yl)-6,9-dioxo-2-oxa-7,10-diaza-1(1,4)-benzenacyclododecaphane-11-carboxamide
InChIKey: BZYUEUWYGRHCPO-YTEMWHBBSA-N
SMILES: O=C1C2=C1C3=CC=C(OC)C=C3C#CC4=C2C=CC(OC)=C4
Biological Activity: Fl-DIBO (fluorogenic dibenzocyclooctyne) is a selective and high sensitivity fluorescent probe to azide compounds. Fl-DIBO can react rapidly with azide compounds to form new highly fluorescent products with a maximum emission wavelength of 469 nm and excitation wavelength of 363 nm. Fl-DIBO can be used to label diazo-tagged proteins without detectable background signal interference[1][2]. Fl-DIBO is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Fl-DIBO | 99.60% | Fl-DIBO (fluorogenic dibenzocyclooctyne) is a selective and high sensitivity fluorescent probe to azide compounds. Fl-DIBO can react rapidly with azide compounds to form new highly fluorescent products with a maximum emission wavelength of 469 nm and excitation wavelength of 363 nm. Fl-DIBO can be used to label diazo-tagged proteins without detectable background signal interference. Fl-DIBO is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
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References
- [1]. Ke Wang, et al. A metal-free turn-on fluorescent probe for the fast and sensitive detection of inorganic azides. Bioorg Med Chem Lett. 2016 Apr 1;26(7):1651-4. [Content Brief]
- [2]. Frédéric Friscourt, et al. Fluorogenic Strain-Promoted Alkyne-Diazo Cycloadditions. Chemistry. 2015 Sep 28;21(40):13996-4001. doi: 10.1002/chem.201502242. Epub 2015 Aug 18. [Content Brief]
