141136-85-8
141136-85-8
Chemical Structure
Protease-Activated Receptor-1, PAR-1 Agonist
- CAS No.: 141136-85-8
- Formula:C35H58N10O9
- Molecular Weight:762.90
InChIKey: HIKQWJFKUWYBNJ-GSAYKZDLSA-N
SMILES: O=C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(N)=O)C(O)=O)=O)=O)=O)=O)[C@H]([C@H](O)C)N
Biological Activity: Protease-Activated Receptor-1, PAR-1 Agonist is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist corresponds to PAR1 tethered ligand and which can selectively mimic theactions of thrombin via this receptor[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Protease-Activated Receptor-1, PAR-1 Agonist | 99.70% | Protease-Activated Receptor-1, PAR-1 Agonist is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist corresponds to PAR1 tethered ligand and which can selectively mimic theactions of thrombin via this receptor. | ||||||||||||||||||||
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References
- [1]. Stefanie Gödecke, et al. Thrombin-induced ATP release from human umbilical vein endothelial cells. Am J Physiol Cell Physiol. 2012 Mar 15;302(6):C915-23. [Content Brief]
- [2]. Heider I, et al. PAR1-type thrombin receptor stimulates migration and matrix adhesion of human colon carcinoma cells by a PKCepsilon-dependent mechanism. Oncol Res. 2004;14(10):475-482. [Content Brief]
