141283-87-6
141283-87-6
Chemical Structure
Fuzapladib
Synonym(s): IS-741
- CAS No.: 141283-87-6
- Formula:C15H20F3N3O3S
- Molecular Weight:379.40
IUPAC Name: N-(2-(ethylsulfonamido)-5-(trifluoromethyl)pyridin-3-yl)cyclohexanecarboxamide
InChIKey: TUWCZRFHNIOVTC-UHFFFAOYSA-N
SMILES: O=C(C1CCCCC1)NC2=CC(C(F)(F)F)=CN=C2NS(=O)(CC)=O
Biological Activity: Fuzapladib (IS-741), an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site[1][2].
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Fuzapladib | 98.75% | Fuzapladib (IS-741), an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site. | ||||||||||||||||||||
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