141284-73-3
Chemical Structure
Fuzapladib sodium
Synonym(s): IS-741 sodium
- CAS No.: 141284-73-3
- Formula:C15H20F3N3NaO3S
- Molecular Weight:402.39
IUPAC Name: N-(2-(ethylsulfonamido)-5-(trifluoromethyl)pyridin-3-yl)cyclohexanecarboxamide, sodium salt
InChIKey: NRRNIBATADCYRE-UHFFFAOYSA-N
SMILES: O=C(C1CCCCC1)NC2=CC(C(F)(F)F)=CN=C2NS(=O)(CC)=O.[Na]
Biological Activity: Fuzapladib (IS-741) sodium, an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib sodium is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib sodium exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site[1][2].
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Fuzapladib sodium | 99.61% | Fuzapladib (IS-741) sodium, an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib sodium is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib sodium exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site. | ||||||||||||||||||||
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