1414-45-5
Chemical Structure
Nisin
- CAS No.: 1414-45-5
- Formula:C143H230N42O37S7
- Molecular Weight:3354.07
SMILES: O=C1N2[C@@](CCC2)(C(=O)NCC(=O)N[C@H](C(N[C@H](C(N[C@@H]3[C@H](C)SC[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]4[C@H](C)SC[C@]5(C(=O)N[C@@H](CC6=CN=CN6)C(=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC7=CN=CN7)C(N[C@H](C(NC(C(N[C@@H](CCCCN)C(O)=O)=O)=C)=O)C(C)C)=O)=O)[C@H](CC)C)=O)CO)=O)CS[C@@H](C)[C@@](NC(=O)[C@H](C)NC4=O)(C(=O)N5)[H])[H])=O)CCCCN)=O)CCSC)=O)CC(N)=O)=O)NC(=O)CNC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)CNC3=O)=O)CCCCN)=O)CS[C@@H](C)[C@H]1NC(=O)[C@H]8NC(=O)[C@H](CC(C)C)NC(=O)C(=C)NC(=O)[C@]([C@H](CC)C)(NC(=O)[C@H](NC(/C(/NC([C@H]([C@H](CC)C)N)=O)=C/C)=O)CSC8)[H])[H]
Biological Activity: Nisin is a bacteriocin produced by a group of Gram-positive bacteria that belongs to Lactococcus and Streptococcus species. Nisin has antibacterial and anti-inflammatory activity[1][2][3].
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Nisin | Nisin is a bacteriocin produced by a group of Gram-positive bacteria that belongs to Lactococcus and Streptococcus species. Nisin has antibacterial and anti-inflammatory activity. | |||||||||||||||||||||
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References
- [1]. Shin JM, et al. Biomedical applications of nisin. J Appl Microbiol. 2016 Jun;120(6):1449-65. [Content Brief]
- [2]. de Carvalho Clímaco M, et al. Nisin Induces Cell-Cycle Arrest in Free-Living Amoebae Acanthamoeba castellanii. Acta Parasitol. 2022 Mar;67(1):511-517. [Content Brief]
- [3]. Jia Z, et al. Nisin reduces uterine inflammation in rats by modulating concentrations of pro- and anti-inflammatory cytokines. Am J Reprod Immunol. 2019 May;81(5):e13096. [Content Brief]
