1415033-91-8
1415033-91-8
Chemical Structure
TB-9
- CAS No.: 1415033-91-8
- Formula:C55H76N8O12
- Molecular Weight:1041.24
SMILES: O=C(OCC1=CC=CC=C1)N[C@@H](C(C)C)C(N(C)[C@@H](CCC(N)=O)C(N[C@@H](CC2=CC=CC=C2)[C@@H](O)CC(N[C@@H](CC(C)C)C(N[C@@H](C)C(N(C)[C@H](CC3=CC=CC=C3)C(N4[C@@H](CCC4)C(OC)=O)=O)=O)=O)=O)=O)=O
Biological Activity: TB-9, a Tasiamide B (HY-N15154) derivative, is a potent cathepsin D, cathepsin E, and BACE1 inhibitor with IC50s of 0.0783 nM, 0.724 nM, and 54.2 nM, respectively[1].
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TB-9 | TB-9, a Tasiamide B (HY-N15154) derivative, is a potent cathepsin D, cathepsin E, and BACE1 inhibitor with IC50s of 0.0783 nM, 0.724 nM, and 54.2 nM, respectively. | |||||||||||||||||||||
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