141696-11-9
Chemical Structure
Galanin (2-29) (rat)
Synonym(s): Rat galanin(2-29)
- CAS No.: 141696-11-9
- Formula:C139H208N42O40
- Molecular Weight:3107.40
SMILES: OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(NCC(N2[C@@H](CCC2)C(N[C@H](C(N[C@@H](C)C(N[C@]([C@@H](C)CC)([H])C(N[C@@H](CC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(N[C@H](C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@H](C(NCC(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)[C@H](O)C)=O)=O)=O)CC3=CNC=N3)=O)=O)=O)=O)CC4=CC=CC=C4)=O)=O)=O)CC5=CNC=N5)=O)=O)=O)=O)=O)CC6=CNC=N6)=O)=O)=O)=O)=O)NC(CNC([C@H](C)NC([C@H](CO)NC([C@H](CC(N)=O)NC([C@H](CC(C)C)NC([C@@]([C@H](O)C)([H])NC([C@@H](N)CC7=CNC8=C7C=CC=C8)=O)=O)=O)=O)=O)=O)=O
Biological Activity: Galanin (2-29) (rat) inhibits rat pancreatic protein and CCK-8-stimulated amylase secretion. Galanin (2-29) (rat) is an GAL2R agonist (Ki: 3.5 nM)[1][2].
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Galanin (2-29) (rat) | Galanin (2-29) (rat) inhibits rat pancreatic protein and CCK-8-stimulated amylase secretion. Galanin (2-29) (rat) is an GAL2R agonist (Ki: 3.5 nM). | |||||||||||||||||||||
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References
- [1]. Rossowski WJ, et al. Galanin: structure-dependent effect on pancreatic amylase secretion and jejunal strip contraction. Eur J Pharmacol. 1993 Aug 24;240(2-3):259-67. [Content Brief]
- [2]. Wang S, et al. Molecular cloning and pharmacological characterization of a new galanin receptor subtype. Mol Pharmacol. 1997 Sep;52(3):337-43. [Content Brief]
