1420043-66-8
1420043-66-8
Chemical Structure
DL-threo-Chloramphenicol-d5
- CAS No.: 1420043-66-8
- Formula:C11H7D5Cl2N2O5
- Molecular Weight:328.16
IUPAC Name: 2,2-dichloro-N-(1,3-dihydroxy-1-(4-nitrophenyl-2,3,5,6-d4)propan-2-yl-1-d)acetamide
InChIKey: WIIZWVCIJKGZOK-NEKQGQCZSA-N
SMILES: [2H]C1=C(C([2H])=C(C([N+]([O-])=O)=C1[2H])[2H])C(O)(C(CO)NC(C(Cl)Cl)=O)[2H]
Biological Activity: DL-threo-Chloramphenicol-d5 is a deuterium labeled DL-threo-Chloramphenicol. DL-threo-Chloramphenicol is the racemate of Chloramphenicol.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DL-threo-Chloramphenicol-d5 | 99.2% | DL-threo-Chloramphenicol-d5 is a deuterium labeled DL-threo-Chloramphenicol. DL-threo-Chloramphenicol is the racemate of Chloramphenicol. | ||||||||||||||||||||
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Chloramphenicol (Standard) | 99.67% | Chloramphenicol (Standard) is the analytical standard of Chloramphenicol. This product is intended for research and analytical applications. Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. Chloramphenicol shows antibacterial activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research. | ||||||||||||||||||||
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Chloramphenicol-d4 | Chloramphenicol-d4 is deuterium labeled Chloramphenicol. Chloramphenicol, a broad-spectrum antibiotic, acts as a potent inhibitor of bacterial protein biosynthesis. Chloramphenicol acts primarily on the 50S subunit of bacterial 70S rihosomes and inhibits peptide bond formation by suppressing peptidyl transferase activity. | |||||||||||||||||||||
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Threo-Chloramphenicol-d6 | Threo-Chloramphenicol-d6 is the deuterium labeled Chloramphenicol. Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. Chloramphenicol shows antibacterial activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research. | |||||||||||||||||||||
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Chloramphenicol-d5-2 | Chloramphenicol-d5-2 is the deuterium labeled Chloramphenicol (HY-B0239). Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. | |||||||||||||||||||||
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Chloramphenicol-d5 | 99.90% | Chloramphenicol-d5 is the deuterium labeled Chloramphenicol. Chloramphenicol is a broad-spectrum antibiotic against bacterial infections. | ||||||||||||||||||||
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Chloramphenicol | 99.96% | Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. Chloramphenicol shows antibacterial activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research. | ||||||||||||||||||||
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3-Nitro-L-tyrosine-d3 | 99.0% | 3-Nitro-L-tyrosine-d3 is the deuterium labeled 3-Nitro-L-tyrosine (HY-113248). 3-Nitro-L-tyrosine serves as a biomarker of oxidative stress. 3-Nitro-L-tyrosine attenuates the pressor and vasoconstrictive effects of angiotensin II by inhibiting the α1-adrenergic receptor-mediated signaling pathway, and participates in hemodynamic regulation under pathological conditions such as inflammation and ischemia. 3-Nitro-L-tyrosine can be used in studies related to atherosclerosis, ischemia-reperfusion and sepsis. | ||||||||||||||||||||
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Chloramphenicol 3-acetate | 98.97% | Chloramphenicol 3-acetate is the main intermediate in the biodegradation of CAP, formed by the acetylation of the 3-hydroxy group of CAP through chloramphenicol acetyltransferase, this is a common resistance mechanism that microbes have against chloramphenicol. | ||||||||||||||||||||
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L-(+)-threo-Chloramphenicol | 99.73% | L-(+)-threo-Chloramphenicol ((+)-Chloramphenicol) is the S,S-stereoisomer of Chloramphenicol (HY-B0239). L-(+)-Threo-chloramphenicol inhibits protein synthesis in reticulocytes. L-(+)-threo-Chloramphenicol also inhibits the oxidative activity of isolated mitochondria. | ||||||||||||||||||||
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L-erythro-Chloramphenicol | L-erythro-Chloramphenicol acts as a powerful inhibitor of electron transport. | |||||||||||||||||||||
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Corynecin II | Corynecin II is a kind of biochemical reagent. | |||||||||||||||||||||
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Corynecin III | Corynecin III is a Chloramphenicol (HY-B0239)-like antibiotic, which is found in Corynebacterium. Corynecin III inhibits the growth of Gram-positive and Gram-negative bacteria with MIC values of 2.6-83 μg/mL. | |||||||||||||||||||||
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Corynecin I | Corynecin I is an antibiotic produced by Corynebacterium hydrocarboclastus, and its precursor (D-(-) threo-p-amino phenyl serinol-N-acetylamine) has a minimal inhibitory effect on the synthesis of Corynecin from mevalonic acid. | |||||||||||||||||||||
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Chloramphenicol 1-acetate | Chloramphenicol 1-acetate (Compound Ⅲ) is a microbial transformation product of Chloramphenicol (HY-B0239) by Streptomyces coelicolor. Chloramphenicol 1-acetate is the major product of Chloramphenicol acetyltransferase I (CATI) by regioselective acetylation of C21 hydroxy groups in steroids. | |||||||||||||||||||||
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m-Chloramphenicol | m-Chloramphenicol (m-threo-Chloramphenicol) is an impurity of Chloramphenicol. Chloramphenicol, a broad-spectrum antibiotic, acts as a potent inhibitor of bacterial protein biosynthesis. | |||||||||||||||||||||
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N-Lactoyl-phenylalanine-d5 | N-Lactoyl-phenylalanine-d5 (Lac-Phe-d5) is the deuterium labeled N-Lactoyl-phenylalanine (HY-150012). N-Lactoyl-phenylalanine, a N-lactoyl-amino acid, is a blood-derived signaling metabolite that can be induced by exercise. N-Lactoyl-phenylalanine can reduce obesity and improve glucose tolerance. | |||||||||||||||||||||
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Thiamphenicol-d3 | 99.51% | Thiamphenicol-d3 is a deuterium labeled Thiamphenicol. Thiamphenicol, a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria). | ||||||||||||||||||||
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Thiorphan-d7 | Thiorphan-d7 is the deuterium labeled Thiorphan. Thiorphan is a selective NEP (neprilysin) inhibitor with an IC50 of 6.9 nM. | |||||||||||||||||||||
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(Rac)-Bromamphenicol | (Rac)-Bromamphenicol is the racemate of Bromamphenicol (HY-W686760). Bromamphenicol (Compound Ib) is a derivative of Chloramphenicol (HY-B0239), and exhibits antibacterial activity. Bromamphenicol binds to S50 ribosomal subunit, interfers with the activity of peptidyl transferase, and exhibits inhibitory activity against protein synthesis. | |||||||||||||||||||||
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Bromamphenicol | Bromamphenicol (Compound Ib) is a derivative of Chloramphenicol (HY-B0239), and exhibits antibacterial activity. Bromamphenicol binds to S50 ribosomal subunit, interfers with the activity of peptidyl transferase, and exhibits inhibitory activity against protein synthesis. | |||||||||||||||||||||
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