1420777-30-5
1420777-30-5
Chemical Structure
Microgrewiapine A
- CAS No.: 1420777-30-5
- Formula:C17H29NO
- Molecular Weight:263.42
IUPAC Name: (2S,3R,6S)-6-((1E,3E,5E)-deca-1,3,5-trien-1-yl)-1,2-dimethylpiperidin-3-ol
InChIKey: ZBJGGLXQNXXXRO-VCZRHBNQSA-N
SMILES: CCCC/C=C/C=C/C=C/[C@H]1N([C@H]([C@@H](CC1)O)C)C
Biological Activity: Microgrewiapine A is an antagonist of nAChR. Microgrewiapine A inhibits hα4β2 and hα3β4 activity with 60% and 70% inhibition, respectively. Microgrewiapine A has selective cytotoxic against HT-29 human colon cancer cells with an IC50 of 6.8 μM[1].
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Microgrewiapine A | Microgrewiapine A is an antagonist of nAChR. Microgrewiapine A inhibits hα4β2 and hα3β4 activity with 60% and 70% inhibition, respectively. Microgrewiapine A has selective cytotoxic against HT-29 human colon cancer cells with an IC50 of 6.8 μM. | |||||||||||||||||||||
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