14215-68-0
Chemical Structure
N-Acetyl-D-galactosamine, 98%
- CAS No.: 14215-68-0
- Formula:C8H15NO6
- Molecular Weight:221.21
IUPAC Name: N-((2S,3R,4R,5R,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide
InChIKey: OVRNDRQMDRJTHS-CBQIKETKSA-N
SMILES: CC(N[C@@H]1[C@H]([C@H]([C@H](O[C@@H]1O)CO)O)O)=O
Biological Activity: N-Acetyl-D-galactosamine (GalNAc) is a terminal essential amino sugar derived from galactose and forms the antigens of blood group A in humans. N-Acetyl-D-galactosamine (GalNAc) interact with Soya bean agglutinin (SBA), hence decreasing the effects of SBA on cellular membrane permeability and tight junction protein expression in piglets[1]. N-Acetyl-D-galactosamine (GalNAc) inhibits the hemagglutinating activity by the lectin[2].
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N-Acetyl-D-galactosamine, 98% | 99.85% | N-Acetyl-D-galactosamine (GalNAc) is a terminal essential amino sugar derived from galactose and forms the antigens of blood group A in humans. N-Acetyl-D-galactosamine (GalNAc) interact with Soya bean agglutinin (SBA), hence decreasing the effects of SBA on cellular membrane permeability and tight junction protein expression in piglets. N-Acetyl-D-galactosamine (GalNAc) inhibits the hemagglutinating activity by the lectin. | ||||||||||||||||||||
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References
- [1]. Zhao B, et al. N-Acetyl-d-galactosamine prevents soya bean agglutinin-induced intestinal barrier dysfunction in intestinal porcine epithelial cells. J Anim Physiol Anim Nutr (Berl). 2019 Jul;103(4):1198-1206. [Content Brief]
- [2]. Sadanandan R, et al. Isolation, Purification and Characterisation of a D-galactose and N-acetyl-D-galactosamineSpecific Lectin from Marine Sponge Fasciospongia cavernosa. Protein Pept Lett. 2018;25(9):871-877. [Content Brief]
