1421680-54-7
Chemical Structure
Cys-GE11
- CAS No.: 1421680-54-7
- Formula:C78H102N18O20S
- Molecular Weight:1643.82
InChIKey: WXXZQIUXLZJHFG-UDJXQYAUSA-N
SMILES: O=C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CC2=CNC=N2)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CC5=CC=C(C=C5)O)C(NCC(N[C@@H](CC6=CC=C(C=C6)O)C(N[C@@H]([C@H](O)C)C(N7[C@@H](CCC7)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](C(C)C)C(N[C@@H]([C@@H](C)CC)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CS)N
Biological Activity: Cys-GE11 is an N-terminal modified GE11 (HY-P10128) with cysteine (Cys) added. Cys-GE11 can be coupled through the thiol group of Cys. Cys-GE11 can be linked to PEG-P (TMC-DTC) through the N-terminus of cysteine to form a targeted polymer. Cys-GE11 can target cells with high EGFR expression (such as SMMC-7721 cells). Cys-GE11 can significantly enhance drug enrichment at the tumor site and exhibit low toxicity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Cys-GE11 | 98.03% | Cys-GE11 is an N-terminal modified GE11 (HY-P10128) with cysteine (Cys) added. Cys-GE11 can be coupled through the thiol group of Cys. Cys-GE11 can be linked to PEG-P (TMC-DTC) through the N-terminus of cysteine to form a targeted polymer. Cys-GE11 can target cells with high EGFR expression (such as SMMC-7721 cells). Cys-GE11 can significantly enhance drug enrichment at the tumor site and exhibit low toxicity. | ||||||||||||||||||||
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