1423758-00-2
Chemical Structure
Piflufolastat
Synonym(s): DCFPYL
- CAS No.: 1423758-00-2
- Formula:C18H23FN4O8
- Molecular Weight:442.40
IUPAC Name: (((S)-1-carboxy-5-(6-fluoronicotinamido)pentyl)carbamoyl)-L-glutamic acid
InChIKey: OLWVRJUNLXQDSP-RYUDHWBXSA-N
SMILES: O=C(CC[C@H](NC(N[C@@H](CCCCNC(C1=CC=C(N=C1)F)=O)C(O)=O)=O)C(O)=O)O
Biological Activity: Piflufolastat (DCFPYL) can be used for the preparation of piflufolastat F 18 (DCFPyL F-18). Piflufolastat F-18 (DCFPyL F-18) is an 18F-labeled imaging agent. Piflufolastat F-18 can be used for positron emission tomography (PET) targeting prostate-specific membrane antigen (PSMA). Piflufolastat can be used for imaging of prostate cancer[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Piflufolastat | 99.18% | Piflufolastat (DCFPYL) can be used for the preparation of piflufolastat F 18 (DCFPyL F-18). Piflufolastat F-18 (DCFPyL F-18) is an 18F-labeled imaging agent. Piflufolastat F-18 can be used for positron emission tomography (PET) targeting prostate-specific membrane antigen (PSMA). Piflufolastat can be used for imaging of prostate cancer. | ||||||||||||||||||||
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References
- [1]. Keam SJ, et al. Piflufolastat F 18: Diagnostic First Approval. Mol Diagn Ther. 2021;25(5):647-656. [Content Brief]
- [2]. Chen Y, et al. 2-(3-{1-Carboxy-5-[(6-[18F]fluoro-pyridine-3-carbonyl)-amino]-pentyl}-ureido)-pentanedioic acid, [18F]DCFPyL, a PSMA-based PET imaging agent for prostate cancer. Clin Cancer Res. 2011;17(24):7645-7653. [Content Brief]
